(slang) A cramp-like ache in the testicles and prostate region caused by prolonged sexual arousal; testicles experiencing such an ache.
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(US, dated, slang) Buboes (in a person of any sex) caused by a sexually transmitted infection; the infection that causes them.
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(slang, figuratively) Unfulfilled sexual desire.
It invades lymphatics, is carried to the inguinal lymph nodes, where multiple abscesses, buboes, or "blue balls" appear. A brawny edema of the labia, with deeply penetrating destructive ulcers may occur in the late stages.
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Regional slang from around the English-speaking world — British, Australian, Irish, Caribbean, Nigerian, Filipino, AAVE, and the hyphenated-English dialects that make the internet sound local.
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