Homeslice is warm, affectionate slang for a close friend — especially someone from your neighborhood, your block, or your crew. It's an extension of the 'homie/homeboy' family of terms, with 'slice' adding a bit of playful flavor, like you're calling someone your personal piece of the neighborhood pie. The word hit its peak in 1990s American slang but has had a notable resurgence in ironic and nostalgic use online, where people deploy it with varying degrees of sincerity and humor.
What's good, homeslice? Haven't seen you since the summer.
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(slang) A close friend from the neighborhood.
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Regional slang from around the English-speaking world — British, Australian, Irish, Caribbean, Nigerian, Filipino, AAVE, and the hyphenated-English dialects that make the internet sound local.
See all Regional & Other slang on Slangora.