(slang) Mechanically enhanced for high performance; souped-up.
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(slang, usually followed by "on") Drugged; intoxicated.
You could see in his eyes that he was hopped up on goofballs.
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Regional slang from around the English-speaking world — British, Australian, Irish, Caribbean, Nigerian, Filipino, AAVE, and the hyphenated-English dialects that make the internet sound local.
See all Regional & Other slang on Slangora.