(chiefly, North America) A length of sawn wood of cross section nominally 2 inches by 4 inches (actual dimensions 1½ × 3½ in modern use), most often employed as structural framing lumber (dimensional lumber).
Well, Moses stood on the Red Sea shore, And smote the water with a two by four
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(chiefly, North America, dated) A small, modest building.
Moses stood on the Red Sea shore, smotin' that water with a two by four
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Regional slang from around the English-speaking world — British, Australian, Irish, Caribbean, Nigerian, Filipino, AAVE, and the hyphenated-English dialects that make the internet sound local.
See all Regional & Other slang on Slangora.