Pusley is a dialectal American term for purslane (Portulaca oleracea), the fleshy-leaved weed common in gardens and disturbed soil across the US. Typically used in rural contexts, especially in the South and Midwest, where the plant is familiar as both a persistent garden pest and an edible green. The register is homey and vernacular — you wouldn't hear it in a botanical lecture, but you might in a kitchen garden conversation. It carries a slight old-fashioned flavour, the word of someone who learned it from their grandmother rather than a field guide.
Grandma always said to pull the pusley before it set seed or you'd be fighting it all summer.
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(US, dialect) purslane (Portulaca oleracea).
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Regional slang from around the English-speaking world — British, Australian, Irish, Caribbean, Nigerian, Filipino, AAVE, and the hyphenated-English dialects that make the internet sound local.
See all Regional & Other slang on Slangora.