Any screw used to hold or adjust a setting, via fixation in a certain location or position: frequently a headless one, but may also be any other machine screw or thumb screw used for the purpose of setting.
1847, editorial staff, MACHINE FOR PUNCHING COPPER SHEETS in "Scientific American", series 1, Volume 3, Issue 10, page 73
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(NZ) A screw with a head, usually hexagonal, like a bolt but without a shank to allow it to screw into material rather than take a nut; a tap bolt.
: ...upon which the sheet to be reduced in width is placed and held firm by set screws, the part to be cut off falls upon the sinkage....
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