(transitive, slang) To kill.
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(transitive) To remove, as a discount or estimate.
The mobsters hired the guy to knock off their enemies.
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(ambitransitive, slang) To halt one's work or other activity.
I think I'll knock off for the evening and go to bed.
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Regional slang from around the English-speaking world — British, Australian, Irish, Caribbean, Nigerian, Filipino, AAVE, and the hyphenated-English dialects that make the internet sound local.
See all Regional & Other slang on Slangora.