Short for "opposition research" — the campaign-staffer tradecraft of digging up damaging information about political opponents. Standard shorthand in US political-Twitter / Bluesky discourse since at least the late 2000s. Wider sports use: in British football, "the oppo" = the opposing team ("watching the oppo on tape this week"). Context disambiguates.
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Viral internet speak — memes, ratios, main-character moments, and the algospeak of every platform from Twitter to Reddit to TikTok comment sections.
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someone in the oppo shop must have leaked that file, no way that surfaces randomly
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