A dated British colloquial (and humorous) pronunciation-based corruption of rheumatism — the painful joint condition. Screwmatics captures the way older working-class British English speakers sometimes pronounced rheumatism, and the screw part even implies the screwing, grinding pain of the condition. It's affectionate, slightly comedic, and now mostly found in period fiction and historical dialect writing.
"Me screwmatics are playing up something awful in this cold," he muttered, rubbing his knees.
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(British, colloquial, dated) Rheumatism.
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Regional slang from around the English-speaking world — British, Australian, Irish, Caribbean, Nigerian, Filipino, AAVE, and the hyphenated-English dialects that make the internet sound local.
See all Regional & Other slang on Slangora.